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Kirkman's Trimethylglycine (TMG) with Folinic Acid & Methyl B-12 Hypoallergenic Capsules

Many clinicians are now utilizing higher doses of TMG. Kirkman's current TMG products at 175 mg. require individuals to swallow too many capsules to meet the physicians' recommended intake. Kirkman has responded with a TMG 500 mg. Hypoallergenic Capsule with Folinic Acid and B-12 (methyl). The daily dose in these situations can now be reduce...

Kirkman's Trimethylglycine (TMG) with Folinic Acid & Methyl B-12 Hypoallergenic Capsules

Many clinicians are now utilizing higher doses of TMG. Kirkman's current TMG products at 175 mg. require individuals to swallow too many capsules to meet the physicians' recommended intake. Kirkman has responded with a TMG 500 mg. Hypoallergenic Capsule with Folinic Acid and B-12 (methyl). The daily dose in these situations can now be reduced to one or two capsules making compliance easier and more convenient.

Folic acid intake and levels in the body must be adequate for TMG to work biochemically. For this reason, some physicians recommend a TMG supplement containing folic acid in the form of folinic acid. To be active in the body, folic acid has to be reduced twice by folate reductase enzymes and is converted to tetrahydrofolate after which a methyl group is added to the tetrahydrofolate. In some individuals, the use of natural folinic acid may be more beneficial than folic acid, because folinic acid already has attached four hydrogen atoms and one methyl group, thereby short cutting the complicated biochemical processes that assist purine and nucletide synthesis, which are so important in cell perception and response. For that reason, some doctors are recommending TMG with folinic acid instead of the folic acid form of folate.

Because folic acid can sometimes mask a B-12 deficiency, vitamin B-12 has been included as well. It is also known that vitamin B-12 works synergistically with folic acid. The most active form of B-12 in folate chemistry is methylcobalamin and Kirkman utilizes this form of B-12 in this product. This new TMG product may better assist methionine metabolism, methylation, and folate chemistry.