Supplementation with a higher amount of alpha-lipoic acid – an important antioxidant in both fat- and water-soluble tissues Alpha-lipoic acid (ALA) has its own antioxidant activity and also helps recycle other antioxidants, including glutathione, an essential antioxidant for liver detoxification. Alpha-lipoic acid has historically provided benefit after toxic insults to the liver. Alpha-lipoic acid is also a cofactor nutrient for mitochondrial function, thus supporting energy production in the cells. Studies indicate higher amounts (600-1,800 mg) of alpha-lipoic acid may be most effective for neurological support. Thiocid-300 provides 300 mg alpha-lipoic acid per capsule in situations where these higher amounts are desired.