Refrigerated Shipping (Optional Upgrade)

For optimal product stability, especially during warm or humid weather, we recommend FedEx Overnight shipping with ice packs and a cooler. It’s a $29.99 flat rate within the continental U.S., already $10–$15 below our actual cost.

Free Ground Shipping (Default Option)

We also offer free ground shipping within the U.S. year-round (without ice packs or a cooler). This option is generally fine in cooler weather, but we don’t recommend it during periods of high heat.

Orders ship from Cleveland, Ohio, typically Monday through Wednesday to avoid weekend delays.

International Orders

We offer non-refrigerated international shipping for an additional fee. Refrigerated shipping is not available for international destinations.

Important Notes

• 
  Overnight orders must ship to a street address (no PO boxes).
  
• 
  Refrigerated items cannot be returned or refunded.

Benefits and Features

• Enhanced support for healthy GI and immune system function
• Optimize gastrointestinal health
• Spore-forming probiotics such as Bacillus are vital to the food chain as they have the intrinsic ability to produce a multitude of enzymes, secretory proteins, antimicrobial compounds, vitamins, and carotenoids.

100% spore-based probiotic blend that helps recondition the gut by encouraging microbial diversity and preserving essential health promoting commensal gut bacteria.

Detail Overview

Ther-Biotic® Biospora™ is a powerful blend of genetically certified Bacillus coagulans and B. subtilis species formulated to provide unique probiotic support for healthy gastrointestinal and immune function. Spore-forming bacilli have often been referred to as soil-based microorganisms because of their ubiquitous presence on the earth. When isolated from the human GI tract, spore-forming bacilli have long been thought to be transient bacteria. However, current research shows that Bacillus species are present in the GI tract in numbers higher than can be explained by ingestion alone. Germination of Bacillus spores within the human small intestine and transient colonization is now thought to be part of the normal life cycle of human-associated Bacillus species providing specific stimuli for healthy GI and immune system development and function. Each capsule of Ther-Biotic® BioSpora™ supplies a total of 2 billion CFUs of B. coagulans and B. subtilis spores positively identified through independent 16S ribosomal RNA gene sequencing. The spores are resistant to extremes of heat, ultraviolet radiation, solvents, hydrogen peroxide, and enzymes. The spores withstand stomach acid and germinate in the small intestine within 6 hours of ingestion. Ingested B. coagulans and B. subtilis reside in the human GI tract for up to 7 days following consumption. Ther-Biotic® BioSpora™ is recommended for enhanced support of normal GI and immune function. Ther-Biotic® Biospora™ does not require refrigeration

Caution

Consult your physician if you are pregnant, nursing, have a medical condition, taking prescription drugs or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.

Made without common allergens: milk/casein, eggs, fish, shellfish, peanuts, wheat, gluten, and soybeans. No synthetic colors, flavors, or preservatives. Vegan and non-GMO.

Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.