• Promotes breakdown of dietary histamine‡
• Eat with greater confidence when histamine may be present in food‡
• Reduces gastrointestinal discomfort (occasional diarrhea, bloating and gas) associated with sensitivity to histamine-rich foo

Histamine is a substance found in many foods, such as meats, spinach, fermented foods, avocadoes, nuts, tomatoes and chocolate.  An estimated 1-3% of the population cannot digest dietary histamine efficiently, often because of low intestinal diamine oxidase (DAO), an enzyme in the GI tract that normally breaks down histamine. These individuals often experience gastrointestinal discomfort, headache, skin sensitivity or flushing after consuming histamine-containing foods.¹ Supplementation with DAO enhances DAO activity in the GI tract, promoting breakdown of dietary histamine and reducing gastrointestinal discomfort (occasional diarrhea, bloating and gas) associated with sensitivity to histamine-rich foods.³ DAO may also reduce skin symptoms associated with high intestinal histamine levels.⁶